Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28422000 | 0.82 | GPR84 (0.56) | GPR84HTR2ATDO2TRPM8F7 | |
| SCHEMBL27640766 | 0.79 | MPO (0.56) | GPR84HTR2ATRPM8HTR2C | |
| SCHEMBL351715 | 0.79 | ALDH1A1 (0.58) | GPR84HTR2ATDO2TRPM8F7 | |
| SCHEMBL27640758 | 0.76 | SLC6A4 (0.50) | SLC6A4HTR6SLC6A2SLC6A3 | |
| SCHEMBL10119751 | 0.75 | GPR84 (0.73) | GPR84HTR2ATRPM8F7F3 | |
| SCHEMBL16881530 | 0.75 | HPGD (0.60) | GPR84HTR2ATDO2TRPM8F7 | |
| SCHEMBL16881531 | 0.75 | HPGD (0.60) | GPR84HTR2ATDO2TRPM8F7 | |
| SCHEMBL3621033 | 0.74 | CYP2A6 (0.60) | GPR84 | |
| SCHEMBL6024778 | 0.72 | F7 (0.42) | GPR84HTR2ATDO2F7F3 | |
| SCHEMBL6024776 | 0.72 | F7 (0.42) | GPR84HTR2ATDO2F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1860112-A | 3-amino chroman and 2-amino tetralin derivatives | WYETH CORP (US) | 2006-11-08 | — | — | CN | claimed |
| CN-1860112-A | 3-amino chroman and 2-amino tetralin derivatives | WYETH CORP (US) | 2006-11-08 | — | — | CN | disclosed |