Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | LCAT | P04180 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28160565 | 0.81 | HSD11B1 (0.36) | HSD11B1LCATMALT1TRPA1 | |
| SCHEMBL21645299 | 0.73 | HSD11B1 (0.44) | HSD11B1MALT1 | |
| SCHEMBL23005388 | 0.70 | MALT1 (0.42) | HSD11B1MALT1TRPA1 | |
| SCHEMBL12528898 | 0.69 | MALT1 (0.40) | HSD11B1MALT1TRPA1 | |
| SCHEMBL3740818 | 0.69 | MALT1 (0.40) | MALT1TRPA1 | |
| SCHEMBL951112 | 0.69 | CYP2C19 (0.44) | HSD11B1MALT1 | |
| SCHEMBL29661868 | 0.69 | CYP2C19 (0.44) | HSD11B1MALT1 | |
| SCHEMBL29276397 | 0.69 | HSD11B1 (0.38) | HSD11B1MALT1TRPA1 | |
| SCHEMBL29661865 | 0.69 | CYP2C19 (0.44) | HSD11B1MALT1 | |
| SCHEMBL29661853 | 0.68 | NPFFR1 (0.37) | HSD11B1MALT1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101607957-B | Intermediate for preparing 3-halo-4,5-dihydro-1h-pyrazoles | PONT US DU | 2012-09-26 | — | — | CN | disclosed |
| CN-101607957-A | Be used to prepare 3-halo-4, the intermediate of 5-dihydro-1 h-pyrazole | DU PONT (US) | 2009-12-23 | — | — | CN | disclosed |
| CN-100537561-C | Process for preparing 3-halo-4, 5-dihydro-1H-pyrazoles | DU PONT (US) | 2009-09-09 | — | — | CN | disclosed |
| CN-1826332-A | Process for preparing 3-halo-4, 5-dihydro-1H-pyrazoles | DU PONT (US) | 2006-08-30 | — | — | CN | disclosed |