Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10809702 | 0.80 | NPSR1 (0.48) | PKMKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL7264580 | 0.79 | ALDH1A1 (0.41) | PKMKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL27699779 | 0.79 | KHK (0.49) | PKMKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL807478 | 0.79 | KDM4E (0.62) | PKMKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL1289560 | 0.79 | L3MBTL1 (0.65) | KDM4EALDH1A1HPGDTSHRGAA | |
| SCHEMBL30529287 | 0.79 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL10333722 | 0.79 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL1514476 | 0.77 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDTSHRGAA | |
| SCHEMBL10803255 | 0.76 | ALDH1A1 (0.42) | PKMKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL3835603 | 0.76 | CYP1A2 (0.50) | KDM4EALDH1A1NPSR1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1750823-A | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same | AVANIR PHARMACEUTICALS (US) | 2006-03-22 | — | — | CN | disclosed |