Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | NCK1 | P16333 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22509803 | 0.86 | KDM4E (0.62) | KDM4EALDH1A1GAAPKMHPGD | |
| SCHEMBL27640795 | 0.79 | PKM (0.57) | KDM4EALDH1A1GAAPKMHPGD | |
| SCHEMBL789995 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1GAAPKMHPGD | |
| SCHEMBL789748 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1GAAPKMNPSR1 | |
| SCHEMBL24091986 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1GAAPKMHPGD | |
| SCHEMBL22521377 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1GAAPKMHPGD | |
| SCHEMBL941858 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL29904585 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL14702032 | 0.76 | NCK1 (0.57) | KDM4EALDH1A1GAAHPGDNCK1 | |
| SCHEMBL4864428 | 0.76 | NCK1 (0.57) | KDM4EALDH1A1GAAHPGDNCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020205867-A1 | COMPOUNDS TARGETING PRMT5 | ALIGOS THERAPEUTICS, INC. (US) | 2020-10-08 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |