Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL243327 | 0.81 | MMP12 (0.49) | RAB9AHPGDNPC1ALDH1A1MAPT | |
| Butyric Acid SCHEMBL27839710 | 0.79 | TP53 (0.55) | RAB9AHPGDNPC1ALDH1A1MAPT | |
| SCHEMBL7502932 | 0.79 | PPIB (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| Bicarbonate SCHEMBL7649134 | 0.76 | HPGD (0.64) | RAB9AHPGDNPC1ALDH1A1MAPT | |
| Sebacic Acid SCHEMBL28488143 | 0.76 | MAPT (0.55) | RAB9AHPGDNPC1ALDH1A1MAPT | |
| SCHEMBL41068 | 0.76 | — | — | |
| SCHEMBL23610315 | 0.75 | ALDH1A1 (0.50) | RAB9AHPGDNPC1ALDH1A1MAPT | |
| SCHEMBL27737468 | 0.75 | RAB9A (0.53) | RAB9AHPGDNPC1ALDH1A1MAPT | |
| Oxalic Acid SCHEMBL11574387 | 0.74 | HPGD (0.61) | RAB9AHPGDNPC1ALDH1A1MAPT | |
| Acetic Acid SCHEMBL2680615 | 0.74 | RAB9A (0.61) | RAB9AHPGDNPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103145715-B | Huge ring carboxylic acid and acyl sulfonamides as HCV replication inhibitors | F·霍夫曼-罗须公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |
| CN-1889970-B | Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of HCV replication | INTERMUNE INC | 2012-06-13 | — | — | CN | disclosed |
| CN-101102787-A | Synthetic hyperglycosylated, and hyperglycosylated protease-resistant polypeptide variants, oral formulations and methods of using the same | ALIOS BIOPHARMA INC (US) | 2008-01-09 | — | — | CN | disclosed |
| CN-101039957-A | Synthetic chemokine receptor ligands and methods of use thereof | INTERMUNE INC (US) | 2007-09-19 | — | — | CN | disclosed |
| CN-1889970-A | Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of HCV replication | INTERMUNE INC (US) | 2007-01-03 | — | — | CN | disclosed |