Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL5082527 | 0.88 | TSHR (0.52) | TSHRDAONAPRTCYP1A2MEN1 | |
| Benzoic Acid SCHEMBL28684602 | 0.88 | TSHR (0.52) | TSHRDAONAPRTCYP1A2MEN1 | |
| Benzoic Acid SCHEMBL5079324 | 0.86 | TSHR (0.54) | TSHRDAONAPRTCYP1A2MEN1 | |
| Benzoic Acid SCHEMBL1783800 | 0.84 | TSHR (0.44) | TSHRDAONAPRTCYP1A2MEN1 | |
| Benzoic Acid SCHEMBL11228092 | 0.79 | TSHR (0.58) | TSHRDAONAPRTCYP1A2MEN1 | |
| Terephthalic Acid SCHEMBL27407508 | 0.79 | ALDH1A1 (0.52) | TSHRCYP1A2MEN1KMT2ASRD5A2 | |
| Benzoyl Formic Acid SCHEMBL16046115 | 0.79 | CES2 (0.48) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27545701 | 0.78 | ALDH1A1 (0.38) | TSHRDAONAPRTCYP1A2MEN1 | |
| Benzoic Acid SCHEMBL27677790 | 0.77 | TSHR (0.47) | TSHRDAONAPRTMEN1KMT2A | |
| Benzoic Acid SCHEMBL28997521 | 0.77 | DAO (0.37) | TSHRDAONAPRTCYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1743346-A | Catalyst component for olefinic polymerization and its catalyst | CHINA PETROCHEMICAL CORP (CN) | 2006-03-08 | — | — | CN | disclosed |
| CN-1743348-A | Catalyst component for olefinic polymerization and its catalyst | CHINA PETROCHEMICAL CORP (CN) | 2006-03-08 | — | — | CN | disclosed |