Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27407508 | 0.92 | ALDH1A1 (0.52) | TSHRSRD5A2ALDH1A1HTTMAPT | |
| Benzoyl Formic Acid SCHEMBL16046115 | 0.92 | CES2 (0.48) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL31118434 | 0.88 | TSHR (0.64) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL7632557 | 0.88 | TSHR (0.64) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL4287422 | 0.88 | TSHR (0.64) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2036300 | 0.88 | TSHR (0.64) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28610 | 0.88 | TSHR (0.64) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2028573 | 0.88 | TSHR (0.64) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL16046259 | 0.87 | TSHR (0.47) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL16044416 | 0.87 | TSHR (0.41) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230376-B1 | POLY(VINYL ACETAL) RESIN COMPOSITIONS, LAYERS, AND INTERLAYERS HAVING ENHANCED OPTICAL PROPERTIES | SOLUTIA INC (US) | 2025-09-24 | — | — | EP | disclosed |
| CN-113105690-B | Heterophasic propylene polymer material and use thereof | 住友化学株式会社 | 2024-03-01 | — | — | CN | disclosed |
| CN-111836855-B | Heterophasic propylene polymer material | 住友化学株式会社 | 2023-09-22 | — | — | CN | disclosed |
| CN-115926028-A | Process for producing solid catalyst component for olefin polymerization, process for producing catalyst for olefin polymerization, and process for producing olefin polymer | 住友化学株式会社 | 2023-04-07 | — | — | CN | disclosed |
| CN-110382574-B | Heterophasic propylene polymer material and propylene resin composition | 住友化学株式会社 | 2023-03-31 | — | — | CN | disclosed |
| US-11358376-B2 | Poly(vinyl acetal) resin compositions, layers, and interlayers having enhanced optical properties | SOLUTIA INC. (US) | 2022-06-14 | — | — | US | disclosed |
| CN-114057913-A | Solid catalyst component for olefin polymerization | 住友化学株式会社 | 2022-02-18 | — | — | CN | disclosed |
| CN-113461842-A | Solid catalyst component for olefin polymerization | 住友化学株式会社 | 2021-10-01 | — | — | CN | disclosed |
| CN-113105690-A | Heterophasic propylene polymer material and use thereof | 住友化学株式会社 | 2021-07-13 | — | — | CN | disclosed |
| CN-109563324-B | Heterophasic propylene polymeric material | 住友化学株式会社 | 2021-06-18 | — | — | CN | disclosed |
| CN-103087222-A | Olefin polymerization catalyst, process for producing olefin polymer, polypropylene resin composition and article comprising the same | SUMITOMO CHEMICAL CO | 2013-05-08 | — | — | CN | disclosed |
| CN-101565475-A | Catalyst component and catalyst thereof for olefinic polymerization | CHINA PETROLEUM & CHEMICAL (CN) | 2009-10-28 | — | — | CN | disclosed |
| US-7332455-B2 | Catalyst component and catalyst for olefin polymerization as well as use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-02-19 | — | — | US | disclosed |
| CN-1310963-C | Catalyst component for olefin polymerization reaction and catalyst | CHINA PETROCHEMICAL CORP (CN) | 2007-04-18 | — | — | CN | disclosed |
| EP-1666505-A1 | CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2006-06-07 | — | — | EP | disclosed |
| US-20050119427-A1 | Catalyst component and catalyst for olefin polymerization as well as use thereof | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-06-02 | — | — | US | disclosed |
| US-20050096389-A1 | Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof | CHINA PETROLEUM & CHEMICAL (CN) | 2005-05-05 | — | — | US | disclosed |
| CN-1552741-A | Catalyst component for olefin polymerization reaction and catalyst | 中国石油化工股份有限公司 | 2004-12-08 | — | — | CN | disclosed |
| CN-1446197-A | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids | WARNER LAMBERT CO (US) | 2003-10-01 | — | — | CN | disclosed |
| JP-2001002873-A | VINYL CHLORIDE RESIN COMPOSITION FOR MOLDING PROCESSING | MITSUBISHI CHEMICALS CORP | 2001-01-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096389-A1 | Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof | CBR3, CBR1, OXER1 | TSHR 921/4885DAO 1971/4885NAPRT 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.