Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922840 | 0.90 | PTPRC (0.43) | PTPRCSMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL4920271 | 0.86 | PTGS2 (0.44) | PTPRCSMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL4918870 | 0.85 | MAPT (0.45) | PTPRCSMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL4920472 | 0.83 | RXRA (0.43) | PTPRCSMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL4915494 | 0.82 | MAPT (0.48) | PTPRCSMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL4919949 | 0.79 | FGFR1 (0.51) | PTPRCSMN1; SMN2MAPTTTRCASP3 | |
| SCHEMBL4921071 | 0.75 | TTR (0.61) | PTPRCSMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL27860059 | 0.75 | MAPT (0.44) | PTPRCSMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL11846453 | 0.75 | PTPRC (0.60) | PTPRCSMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL2265496 | 0.74 | TTR (0.62) | PTPRCSMN1; SMN2MAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1842517-A | Fluorene derivatives | ASTELLAS PHARMA INC (JP) | 2006-10-04 | — | — | CN | disclosed |