Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.48 |
| ▸ | WNT3A | P56704 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668302 | 0.89 | ALDH1A1 (0.62) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL10248336 | 0.81 | ALDH1A1 (0.65) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL7180322 | 0.80 | ALDH1A1 (0.72) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL2415331 | 0.79 | HPGD (0.96) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL22721189 | 0.79 | ALDH1A1 (0.83) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL5179083 | 0.78 | HPGD (1.00) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL3383085 | 0.78 | HPGD (1.00) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL3192172 | 0.78 | HPGD (0.70) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL27594290 | 0.78 | ALDH1A1 (0.59) | HPGDALDH1A1LMNANPC1RAB9A | |
| SCHEMBL23859828 | 0.76 | HPGD (0.73) | HPGDALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100349895-C | Pyrrolopyridazine derivatives | ASTELLAS PHARMA INC (JP) | 2007-11-21 | — | — | CN | disclosed |
| CN-1759117-A | Pyrrolopyridazine derivatives | ASTELLAS PHARMA INC (JP) | 2006-04-12 | — | — | CN | disclosed |