SCHEMBL3192172

SCHEMBL3192172

CCCCCC(=O)c1cccs1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.70
LMNA P02545 4/20 0.69
ALDH1A1 P00352 4/20 0.69
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
NPC1 O15118 2/20 0.69
RAB9A P51151 2/20 0.69
POLB P06746 1/20 0.69
HDAC1 Q13547 2/20 0.64
HTT P42858 2/20 0.56
PKM P14618 1/20 0.56
TSHR P16473 1/20 0.56
MAPK1 P28482 1/20 0.56
HSD17B10 Q99714 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
CTNNB1 P35222 5/20 0.55
WNT3A P56704 4/20 0.55
HDAC11 Q96DB2 1/20 0.55
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2787821 0.98 HPGD (0.73) HPGDLMNAALDH1A1MEN1KMT2A
SCHEMBL9046710 0.98 HPGD (0.73) HPGDLMNAALDH1A1MEN1KMT2A
SCHEMBL8972518 0.98 HPGD (0.73) HPGDLMNAALDH1A1MEN1KMT2A
SCHEMBL3183371 0.98 HPGD (0.73) HPGDLMNAALDH1A1MEN1KMT2A
SCHEMBL23859828 0.98 HPGD (0.73) HPGDLMNAALDH1A1MEN1KMT2A
SCHEMBL3176357 0.95 LMNA (0.71) HPGDLMNAALDH1A1MEN1KMT2A
SCHEMBL815576 0.89 HPGD (0.61) HPGDLMNAALDH1A1MEN1KMT2A
Trifluoroacetic Acid SCHEMBL30785213 0.88 HPGD (0.64) HPGDLMNAALDH1A1MEN1KMT2A
SCHEMBL28446591 0.87 HPGD (0.58) HPGDLMNAALDH1A1MEN1KMT2A
SCHEMBL3177576 0.87 LMNA (0.77) HPGDLMNAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3696200-B1 PHOTORESPONSIVE HIGH-MOLECULAR WEIGHT MATERIAL, ADHESIVE, TONER, AND IMAGE FORMING METHOD KONICA MINOLTA INC (JP) 2024-08-28 EP disclosed
US-12037531-B2 Photoresponsive high-molecular weight material, adhesive, toner, and image forming method Konica Minolta, Inc. (JP) 2024-07-16 US disclosed
US-7659411-B2 Process for producing 2-acylthiophene compound SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2010-02-09 US disclosed
CN-100455578-C Process for producing 2-acylthiophene compound SUMITOMO SEIKA CHEMICALS (JP) 2009-01-28 CN disclosed
US-7345079-B2 Treatment of disorder related to low cyclic GMP levels YUNG SHIN PHARMACEUTICALS INDUSTRIAL CO., LTD (TW) 2008-03-18 US disclosed
US-20070149787-A1 Process for producing 2-acylthiophene compound SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2007-06-28 US disclosed
CN-1886396-A Process for producing 2-acylthiophene compound SUMITOMO SEIKA CHEMICALS (JP) 2006-12-27 CN disclosed
EP-1695972-A1 PROCESS FOR PRODUCING 2-ACYLTHIOPHENE COMPOUND SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2006-08-30 EP disclosed
US-20030220385-A1 Treatment of disorder related to low cyclic GMP levels YUNG SHIN PHARMACEUTICALS INDUSTRIAL CO., LT.D (TW) 2003-11-27 US disclosed
US-6387942-B2 PYRAZOLYL COMPOUND; ANTICOAGULANTS, ANTIPROLIFERATIVE AGENT YUNG SHIN PHARMACEUTICAL IND. CO. LTD (TW) 2002-05-14 US disclosed
EP-0364923-B1 MESOMORPHIC COMPOUND, LIQUID CRYSTAL COMPOSITION CONTAINING SAME AND LIQUID CRYSTAL DEVICE USING SAME CANON KABUSHIKI KAISHA (JP) 1993-07-28 EP disclosed
EP-0500072-A1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-08-26 EP disclosed
EP-0499252-A1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-08-19 EP disclosed
US-5118441-A AC stabilization effect; good display and response CANON KABUSHIKI KAISHA (JP) 1992-06-02 US disclosed
US-5116530-A Ferroelectrical optical apparatus containing thiophene groups CANON KABUSHIKI KAISHA (JP) 1992-05-26 US disclosed
EP-0459406-A1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1991-12-04 EP disclosed
EP-0458347-A2 Liquid crystal composition and display device using same CANON KABUSHIKI KAISHA (JP) 1991-11-27 EP disclosed
EP-0392510-A1 Mesomorphic compound, liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-10-17 EP disclosed
EP-0364923-A2 Mesomorphic compound, liquid crystal composition containing same and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-04-25 EP disclosed
US-4467102-A RACEMIC MODIFICATION WITH BRUCINE UBE INDUSTRIES, LTD. (JP) 1984-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220385-A1 Treatment of disorder related to low cyclic GMP levels PDE7A, PDE2A, PDE4A HPGD 226/4885LMNA 1031/4885ALDH1A1 1728/4885
US-20070149787-A1 Process for producing 2-acylthiophene compound AGPAT2, MOGAT2, TPST2 HPGD 2748/4885LMNA 4557/4885ALDH1A1 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.