Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL813078 | 0.82 | THRB (0.52) | THRBTDP1PDK2ALDH1A1P2RX1 | |
| SCHEMBL30345614 | 0.82 | THRB (0.52) | THRBTDP1PDK2ALDH1A1P2RX1 | |
| SCHEMBL16684038 | 0.81 | ALDH1A1 (0.47) | THRBTDP1PDK2ALDH1A1HPGD | |
| SCHEMBL10338059 | 0.80 | PDK2 (0.42) | THRBTDP1PDK2ALDH1A1HSD17B10 | |
| SCHEMBL27623776 | 0.80 | PDK2 (0.43) | THRBTDP1PDK2ALDH1A1HPGD | |
| SCHEMBL30217950 | 0.80 | PDK2 (0.42) | THRBTDP1PDK2ALDH1A1P2RX1 | |
| SCHEMBL7315929 | 0.80 | PDK2 (0.42) | THRBTDP1PDK2ALDH1A1P2RX1 | |
| SCHEMBL27748647 | 0.80 | PDK2 (0.42) | THRBTDP1PDK2ALDH1A1P2RX1 | |
| SCHEMBL2454330 | 0.80 | THRB (0.56) | THRBTDP1PDK2ALDH1A1HPGD | |
| SCHEMBL17816933 | 0.80 | THRB (0.50) | THRBTDP1PDK2ALDH1A1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1769269-A | End-blocked triarylamine and carbazoles material, handling method and uses | UNIV FUDAN (CN) | 2006-05-10 | — | — | CN | disclosed |
| CN-1743409-A | End capped thiofuran small-molecule and polymer material, treating method and use thereof | UNIV FUDAN (CN) | 2006-03-08 | — | — | CN | disclosed |