Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 11/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5046795 | 0.88 | PTGER2 (0.49) | CYP2A6PTGER2CA12CA1CA2 | |
| SCHEMBL6123285 | 0.76 | PDE4A (0.64) | PTGER2PDE4APDE4BPDE4CPDE4D | |
| Water SCHEMBL27643271 | 0.74 | CNR2 (0.63) | PTGER2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13087865 | 0.73 | ALOX5 (0.52) | CYP2A6CYP2C19ALDH1A1TDP1CYP2E1 | |
| SCHEMBL27643325 | 0.73 | PDE4A (0.56) | PTGER2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27643281 | 0.71 | CXCR3 (0.57) | PTGER2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29642739 | 0.71 | ALDH1A1 (0.62) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL4943463 | 0.70 | PTGER2 (0.69) | PTGER2CA12CA1CA2CA4 | |
| SCHEMBL18190156 | 0.70 | PDE4A (0.55) | PTGER2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27614342 | 0.70 | PTGER2 (0.56) | PTGER2CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1859903-A | Use of EP2 selective receptor agonists in medical treatment | PFIZER PROD INC (US) | 2006-11-08 | — | — | CN | disclosed |