Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181917 | 0.81 | MMP1 (0.43) | — | |
| SCHEMBL28622708 | 0.81 | GRIK1 (0.32) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27464717 | 0.79 | TSHR (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5813287 | 0.79 | TSHR (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27510638 | 0.79 | ALDH1A1 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2855141 | 0.79 | TSHR (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18502988 | 0.76 | LMNA (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6432055 | 0.76 | LMNA (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17525660 | 0.76 | LMNA (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28048632 | 0.76 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1711084-A | Substituted 4-alkoxyoxazol derivatives as PPAR agonists | HOFFMANN LA ROCHE (CH) | 2005-12-21 | — | — | CN | disclosed |