Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.38 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644256 | 0.89 | PPARA (0.44) | HRH3PPARAPPARDPPARGEPHX2 | |
| SCHEMBL27644318 | 0.89 | MMP2 (0.41) | HRH3MMP2MMP3TAAR1PPARA | |
| SCHEMBL27644704 | 0.86 | GRM2 (0.48) | TAAR1HDAC1HDAC8 | |
| SCHEMBL27665473 | 0.85 | CTSC (0.40) | BLM | |
| SCHEMBL27644051 | 0.85 | TAAR1 (0.41) | MMP2MMP3TAAR1PPARAPPARD | |
| SCHEMBL27665386 | 0.81 | PPARA (0.42) | HRH3MMP2MMP3TAAR1PPARA | |
| SCHEMBL27644563 | 0.79 | PPARA (0.46) | HRH3PPARAPPARDPPARGEPHX2 | |
| SCHEMBL27665254 | 0.78 | TAAR1 (0.41) | MMP2MMP3TAAR1PPARAPPARD | |
| SCHEMBL27644752 | 0.78 | GRM8 (0.41) | HRH3PPARAFFAR1HDAC8 | |
| SCHEMBL27665810 | 0.78 | GRB2 (0.43) | PPARAPPARGEPHX2BLMFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |