Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27665529 | 0.86 | FFAR1 (0.39) | GRM8GRM4FFAR1HDAC8HDAC6 | |
| SCHEMBL27665487 | 0.85 | MEN1 (0.46) | CES2SLC6A9 | |
| SCHEMBL23009730 | 0.84 | RIPK1 (0.40) | — | |
| SCHEMBL27665501 | 0.83 | GRM8 (0.43) | GRM8GRM4FFAR1CES2CES1 | |
| SCHEMBL27644256 | 0.79 | PPARA (0.44) | SLC6A9DPP4HRH3PPARA | |
| SCHEMBL27644166 | 0.78 | HRH3 (0.40) | FFAR1HDAC8HRH3PPARA | |
| SCHEMBL4983450 | 0.76 | PPARA (0.45) | GRM8GRM4FFAR1HDAC8HDAC6 | |
| SCHEMBL27665810 | 0.76 | GRB2 (0.43) | FFAR1SLC6A9DPP4PPARA | |
| SCHEMBL27644051 | 0.75 | TAAR1 (0.41) | FFAR1HDAC8PPARA | |
| SCHEMBL23891940 | 0.75 | SLC6A2 (0.45) | GRM8GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |