Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 6/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644758 | 0.86 | BLM (0.38) | LMNACYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL27665369 | 0.86 | BLM (0.53) | LMNACYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL27644628 | 0.85 | GABBR2 (0.39) | GABBR2GABBR1CYP1A2MEN1KMT2A | |
| SCHEMBL19320567 | 0.84 | CYP1A2 (0.45) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL27643920 | 0.83 | ALDH1A1 (0.40) | LMNAMEN1KMT2ATSHRNPSR1 | |
| SCHEMBL27665529 | 0.82 | FFAR1 (0.39) | HDAC8HDAC6 | |
| SCHEMBL27644593 | 0.81 | CYP2C9 (0.41) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL27644227 | 0.79 | SMN1; SMN2 (0.39) | LMNACYP2C9CYP1A2CYP2D6MEN1 | |
| SCHEMBL27644860 | 0.79 | TDP1 (0.52) | LMNACYP1A2MEN1KMT2ACYP3A4 | |
| SCHEMBL27665263 | 0.79 | PRCP (0.45) | GABBR2GABBR1LMNACYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |