Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 8/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28758286 | 0.86 | BLM (0.38) | PRCPCYP2C9CYP2D6CYP2C19MEN1 | |
| SCHEMBL27665339 | 0.86 | BLM (0.53) | CYP2C9CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL27665715 | 0.85 | MME (0.41) | CYP2C9CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL27644593 | 0.84 | CYP2C9 (0.41) | PRCPCYP2C9CYP2D6CYP2C19GABBR2 | |
| SCHEMBL28758301 | 0.83 | DPP4 (0.43) | CYP2C19MEN1KMT2ADPP4DPP7 | |
| SCHEMBL27665405 | 0.82 | DPP4 (0.43) | CYP2C9CYP2D6DPP4DPP7 | |
| SCHEMBL27644024 | 0.79 | TDP1 (0.52) | MEN1KMT2ACYP3A4CYP1A2LMNA | |
| SCHEMBL27644015 | 0.79 | BLM (0.36) | CYP2C9CYP2D6MEN1KMT2ACYP3A4 | |
| SCHEMBL28758277 | 0.79 | ALDH1A1 (0.43) | POLBPPARA | |
| SCHEMBL27644259 | 0.79 | GABBR2 (0.46) | CYP2C9CYP2D6CYP2C19GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |