Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28758301 | 0.86 | DPP4 (0.43) | ALDH1A1HPGDCYP2B6MEN1KMT2A | |
| SCHEMBL27644221 | 0.86 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP2B6MEN1KMT2A | |
| SCHEMBL28761460 | 0.84 | ACP3 (0.41) | ALDH1A1HPGDMEN1KMT2AACP3 | |
| SCHEMBL27643926 | 0.84 | HIF1A (0.47) | ALDH1A1HPGDMEN1KMT2AOPRK1 | |
| SCHEMBL27643920 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HPGDCYP2B6MEN1KMT2A | |
| SCHEMBL27644827 | 0.83 | SLC6A2 (0.41) | MEN1KMT2ADPP4DPP7SLC6A2 | |
| SCHEMBL27644593 | 0.82 | CYP2C9 (0.41) | MEN1KMT2ACYP2C19BLMADRB2 | |
| SCHEMBL27643982 | 0.81 | PNMT (0.48) | ALDH1A1MEN1KMT2AACP3GPR139 | |
| SCHEMBL27644044 | 0.78 | PNMT (0.53) | PKMCYP2C19 | |
| SCHEMBL27665200 | 0.78 | GPR139 (0.46) | ALDH1A1TRPM8GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |