Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799231 | 0.82 | KIT (0.55) | KITMAPTACHEKMT2ACNR1 | |
| SCHEMBL25391683 | 0.68 | HTT (0.37) | KITMAPTPDGFRBPDGFRAKMT2A | |
| SCHEMBL2801008 | 0.64 | KIT (0.59) | KITMAPTACHEPOLBCNR1 | |
| SCHEMBL28866006 | 0.64 | HRH4 (0.46) | — | |
| SCHEMBL25272390 | 0.62 | MAP4K4 (0.37) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28792787 | 0.61 | HTR7 (0.39) | MAPTALDH1A1 | |
| SCHEMBL28675131 | 0.61 | ALDH1A1 (0.54) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28794456 | 0.61 | MEN1 (0.39) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25389057 | 0.61 | NCF1 (0.55) | PDGFRBKMT2AALDH1A1 | |
| SCHEMBL13230436 | 0.61 | JAK2 (0.43) | MAPTPOLBKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882347-A | AKT protein kinase inhibitors | ARRAY BIOPHARMA INC (US) | 2006-12-20 | — | — | CN | disclosed |