Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | BRD4 | O60885 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2764450 | 0.84 | HPGD (1.00) | HPGDTSHRHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL17107224 | 0.82 | SMN1; SMN2 (0.71) | HPGDTSHRHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL2763686 | 0.81 | HPGD (0.65) | HPGDTSHRHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL17107149 | 0.81 | USP2 (0.72) | HPGDTSHRHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL6970367 | 0.81 | L3MBTL1 (0.55) | HPGDTSHRHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL2766185 | 0.80 | HPGD (0.64) | HPGDTSHRHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL27923650 | 0.79 | ACHE (0.64) | HPGDTSHRHSD17B10SMN1; SMN2MAPT | |
| Fumaric Acid SCHEMBL6963773 | 0.78 | HPGD (0.58) | HPGDTSHRHSD17B10SMN1; SMN2MAPT | |
| Fumaric Acid SCHEMBL6963761 | 0.78 | HPGD (0.58) | HPGDTSHRHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL24222515 | 0.78 | HPGD (0.57) | HPGDTSHRHSD17B10SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400515-B1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | KOWA CO (JP) | 2010-04-14 | — | — | EP | disclosed |
| CN-100491355-C | Cyclic diamine compound having five-membered cyclic group | KOWA CO (JP) | 2009-05-27 | — | — | CN | disclosed |
| CN-1522250-A | Cyclic diamine compound having five-membered cyclic group | ������������ʽ���� | 2004-08-18 | — | — | CN | disclosed |
| EP-1400515-A1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | Kowa Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6472386-B1 | Cyclic diamine compound with 5-membered ring groups | KOWA CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |