Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27923650 | 0.90 | ACHE (0.64) | L3MBTL1ACHEALDH1A1HSD17B10LMNA | |
| SCHEMBL7055631 | 0.90 | HSD17B10 (0.57) | ACHEALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL6313414 | 0.84 | LMNA (0.72) | L3MBTL1ALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL16789307 | 0.83 | MME (0.61) | L3MBTL1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL2764501 | 0.81 | HPGD (0.73) | L3MBTL1ALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL30058880 | 0.81 | ALDH1A1 (0.53) | ACHEALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL6975573 | 0.80 | ACHE (0.67) | ACHEALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL6976220 | 0.80 | LMNA (0.55) | ACHEALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL6975943 | 0.80 | ACHE (0.64) | ACHEALDH1A1HSD17B10LMNANPSR1 | |
| SCHEMBL6967117 | 0.80 | MAPT (0.71) | L3MBTL1ACHEALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518052-A | Preparation method of acotiamide hydrochloride impurity | 廊坊市泽康医药科技有限公司 | 2020-08-11 | — | — | CN | claimed |
| CN-105753810-B | The refined and preparation method of acotiamide hydrochloride hydrate trihydrate | 浙江新赛科药业有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-105753810-A | Acotiamide hydrochloride trihydrate refining method and acotiamide hydrochloride trihydrate preparation method | 浙江新赛科药业有限公司 | 2016-07-13 | — | — | CN | claimed |
| CN-111518052-A | Preparation method of acotiamide hydrochloride impurity | 廊坊市泽康医药科技有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-111518052-A | Preparation method of acotiamide hydrochloride impurity | 廊坊市泽康医药科技有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-111440128-A | Preparation method of acotiamide hydrochloride impurity | 廊坊市泽康医药科技有限公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-111440128-A | Preparation method of acotiamide hydrochloride impurity | 廊坊市泽康医药科技有限公司 | 2020-07-24 | — | — | CN | disclosed |
| CN-105753810-B | The refined and preparation method of acotiamide hydrochloride hydrate trihydrate | 浙江新赛科药业有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-105753810-A | Acotiamide hydrochloride trihydrate refining method and acotiamide hydrochloride trihydrate preparation method | 浙江新赛科药业有限公司 | 2016-07-13 | — | — | CN | disclosed |
| EP-0870765-B1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARM CO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5981557-A | HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0870765-A1 | AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |