Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 8/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095863 | 0.83 | EPHX2 (0.38) | DCPSCHRM4AKT2EPHX2C5AR1 | |
| SCHEMBL2090842 | 0.80 | EPHX2 (0.34) | DCPSDRD2EPHX2CYP2C9CYP2J2 | |
| SCHEMBL2094572 | 0.71 | EPHX2 (0.35) | EPHX2CYP2C9 | |
| SCHEMBL2094569 | 0.71 | C5AR1 (0.35) | EPHX2C5AR1CYP2C9 | |
| SCHEMBL28758338 | 0.71 | HTR1A (0.43) | DRD2HTR1AHTR2A | |
| SCHEMBL2097959 | 0.71 | NPC1 (0.41) | DCPSCHRM4EPHX2CYP2C9CYP2J2 | |
| SCHEMBL2090670 | 0.71 | KCNN4 (0.43) | CHRM4EPHX2 | |
| SCHEMBL22668657 | 0.68 | HTR2A (0.48) | DRD2HTR1AHTR2A | |
| SCHEMBL2094719 | 0.67 | DCPS (0.39) | DCPSDRD2HTR1AHTR2ACHRM4 | |
| SCHEMBL5016085 | 0.67 | EPHX2 (0.44) | DCPSDRD2EPHX2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |