Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095863 | 0.85 | EPHX2 (0.38) | EPHX2TRPC5DCPS | |
| SCHEMBL27644679 | 0.83 | DRD2 (0.47) | EPHX2CNR1SCN9ATRPC5KMT2A | |
| SCHEMBL2094217 | 0.79 | PDE3B (0.44) | EPHX2SCN9A | |
| SCHEMBL5016238 | 0.77 | DRD2 (0.41) | EPHX2CNR1TRPC5KMT2AMEN1 | |
| SCHEMBL5013289 | 0.75 | KDM4E (0.48) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL5543219 | 0.72 | KMT2A (0.47) | EPHX2CNR1SCN9ATRPC5KMT2A | |
| SCHEMBL5015053 | 0.69 | SIGMAR1 (0.49) | KMT2AMEN1DRD2 | |
| SCHEMBL2095321 | 0.68 | SLC6A3 (0.49) | EPHX2CNR1TRPC5DRD2DCPS | |
| SCHEMBL24093239 | 0.68 | DRD2 (0.60) | EPHX2KMT2AMEN1DRD2DCPS | |
| SCHEMBL2429800 | 0.68 | EPHX2 (0.52) | EPHX2CNR1SCN9ATRPC5DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |