Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27762834 | 0.83 | DRD2 (0.34) | DRD2HTR1AHTR2ASLC6A2SLC6A4 | |
| SCHEMBL27645184 | 0.82 | DRD2 (0.48) | DRD2HTR1AHTR2AMAPTDRD3 | |
| SCHEMBL2092799 | 0.81 | MALT1 (0.34) | DRD2GRM2IRAK4CCR3MAPT | |
| SCHEMBL2092802 | 0.81 | MALT1 (0.34) | DRD2HTR1AHTR2AGRM2CCR3 | |
| SCHEMBL27645199 | 0.80 | HRH3 (0.41) | DRD2HTR1AHTR2ASLC6A2SLC6A4 | |
| SCHEMBL27666219 | 0.78 | HTR1A (0.38) | DRD2HTR1AHTR2AMAPTHTT | |
| SCHEMBL27665965 | 0.74 | HTR1A (0.40) | DRD2HTR1AHTR2AGRM2 | |
| SCHEMBL27666166 | 0.73 | HTR1A (0.43) | DRD2HTR1AHTR2ACCR3MAPT | |
| SCHEMBL28758338 | 0.72 | HTR1A (0.43) | DRD2HTR1AHTR2ACCR3 | |
| SCHEMBL22668657 | 0.72 | HTR2A (0.48) | DRD2HTR1AHTR2ASLC6A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |