Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28116469 | 0.82 | LMNA (0.56) | ALDH1A1HPGDLMNAGAAKMT2A | |
| SCHEMBL27645164 | 0.74 | LMNA (0.60) | ALDH1A1HPGDLMNAGAAKMT2A | |
| SCHEMBL2093375 | 0.74 | SLC6A4 (0.45) | ALDH1A1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5919466 | 0.71 | SLC22A12 (0.42) | PTGES2 | |
| SCHEMBL9590947 | 0.71 | CTNNB1 (0.45) | ALDH1A1GAAHTTL3MBTL1KCNK3 | |
| SCHEMBL16950760 | 0.69 | NFE2L2 (0.47) | HPGDLMNACYP1A2NFE2L2KCNK3 | |
| SCHEMBL2093373 | 0.69 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3RIPK1 | |
| SCHEMBL14892702 | 0.69 | KCNK3 (0.46) | GAAKMT2AL3MBTL1KCNK3KCNK9 | |
| SCHEMBL16958619 | 0.68 | NFE2L2 (0.46) | HPGDLMNACYP1A2NFE2L2KCNK3 | |
| SCHEMBL18112650 | 0.68 | CA1 (0.53) | ALDH1A1HPGDLMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1878777-A | 2,3-dihydro-6-nitroimidazo (2,1-b) oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2006-12-13 | — | — | CN | disclosed |