Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.64 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.64 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.60 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605693 | 0.87 | HPGDS (0.62) | HPGDSALKBH2PRMT5ADAMTS7NPC1 | |
| SCHEMBL4903546 | 0.81 | HPGDS (0.68) | HPGDSALKBH2PRMT5ADAMTS7NPC1 | |
| SCHEMBL27150069 | 0.79 | HPGDS (0.56) | HPGDSALKBH2PRMT5ADAMTS7NPC1 | |
| SCHEMBL27150067 | 0.79 | HPGDS (0.56) | HPGDSALKBH2PRMT5ADAMTS7NPC1 | |
| SCHEMBL7729542 | 0.79 | HPGDS (0.79) | HPGDSALKBH2NPC1MAPTRAB9A | |
| SCHEMBL70281 | 0.79 | ALKBH2 (1.00) | HPGDSALKBH2NPC1MAPTRAB9A | |
| SCHEMBL13926374 | 0.78 | HPGDS (0.62) | HPGDSALKBH2PRMT5NPC1MAPT | |
| SCHEMBL13607996 | 0.78 | HPGDS (0.62) | HPGDSALKBH2PRMT5ADAMTS7NPC1 | |
| SCHEMBL12057532 | 0.77 | KLKB1 (0.71) | HPGDSALKBH2PRMT5MAPK8SMN1; SMN2 | |
| SCHEMBL25910314 | 0.77 | KLKB1 (0.55) | HPGDSALKBH2PRMT5ADAMTS7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1917763-B | N- (2-hydroxymethyl) phenyl-1H-pyrazole-4-carboxamide derivatives and related compounds as microbicidal active ingredients for plant protection and material protection | BAYER CROPSCIENCE AG | 2010-05-05 | — | — | CN | disclosed |
| CN-1917763-A | N- (2-hydroxymethyl) phenyl-1H-pyrazole-4-carboxamide derivatives and related compounds as microbicidal active ingredients for plant protection and material protection | BAYER CROPSCIENCE AG (DE) | 2007-02-21 | — | — | CN | disclosed |