Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HTR1F | P30939 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27646111 | 0.79 | HTR6 (0.32) | HTR6BCHE | |
| SCHEMBL28777649 | 0.77 | HTR6 (0.36) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL28777480 | 0.75 | HDAC3 (0.36) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL27750247 | 0.71 | HTR6 (0.56) | HTR6 | |
| SCHEMBL27643120 | 0.70 | HTR6 (0.53) | HTR6HTR1A | |
| SCHEMBL27771239 | 0.69 | HTR6 (0.56) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL27674782 | 0.68 | PPARG (0.32) | — | |
| SCHEMBL27775885 | 0.64 | HDAC6 (0.47) | HTR6 | |
| SCHEMBL27771342 | 0.64 | HDAC3 (0.36) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL28790455 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1878756-A | Sulfonyltetrahydro-3H-benzo indol-8-amine compounds as 5-hydroxytryptamine-6 ligands | WYETH CORP (US) | 2006-12-13 | — | — | CN | disclosed |