Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27646109 | 0.79 | HTR6 (0.31) | HTR6BCHE | |
| SCHEMBL28777481 | 0.78 | HDAC3 (0.35) | HTR6 | |
| SCHEMBL28777651 | 0.78 | HTR6 (0.34) | HTR6 | |
| SCHEMBL27750248 | 0.72 | HTR6 (0.59) | HTR6 | |
| SCHEMBL27643121 | 0.71 | HTR6 (0.53) | HTR6 | |
| SCHEMBL27771240 | 0.70 | HTR6 (0.56) | HTR6 | |
| SCHEMBL27863452 | 0.68 | NOTUM (0.37) | HTR6BCHE | |
| SCHEMBL27771123 | 0.67 | HTR6 (0.39) | HTR6 | |
| SCHEMBL27750252 | 0.67 | HTR6 (0.39) | HTR6 | |
| SCHEMBL27771343 | 0.66 | HDAC3 (0.35) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1878756-A | Sulfonyltetrahydro-3H-benzo indol-8-amine compounds as 5-hydroxytryptamine-6 ligands | WYETH CORP (US) | 2006-12-13 | — | — | CN | disclosed |