Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163468 | 1.00 | TRPA1 (0.52) | TRPA1TSHRNAAADPP4HTR2A | |
| SCHEMBL6687098 | 1.00 | TRPA1 (0.52) | TRPA1TSHRNAAADPP4HTR2A | |
| SCHEMBL21114422 | 0.81 | TSHR (0.50) | TRPA1TSHRDPP4F2ALDH1A1 | |
| SCHEMBL3968014 | 0.81 | TSHR (0.50) | TRPA1TSHRDPP4F2ALDH1A1 | |
| SCHEMBL27539710 | 0.79 | TSHR (0.48) | TRPA1TSHRDPP4F2IDO1 | |
| SCHEMBL2162532 | 0.79 | TSHR (0.48) | TRPA1TSHRDPP4F2IDO1 | |
| SCHEMBL27625768 | 0.77 | TSHR (0.46) | TRPA1TSHRALDH1A1SMN1; SMN2AKR1C3 | |
| SCHEMBL198464 | 0.77 | TSHR (0.46) | TRPA1TSHRALDH1A1SMN1; SMN2AKR1C3 | |
| SCHEMBL198465 | 0.77 | TSHR (0.46) | TRPA1TSHRALDH1A1SMN1; SMN2AKR1C3 | |
| SCHEMBL2163397 | 0.77 | TSHR (0.46) | TRPA1TSHRDPP4F2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100445375-C | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AG (DE) | 2008-12-24 | — | — | CN | claimed |
| CN-1753990-A | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AG (DE) | 2006-03-29 | — | — | CN | claimed |
| CN-103880625-B | Method for preparing D, L-mandelic acid and derivative of D, L-mandelic acid | CHONGQING UNISPLENDOUR INTERNAT CHEMICAL CO LTD | 2015-07-22 | — | — | CN | disclosed |
| CN-103880625-A | Method for preparing D, L-mandelic acid and derivative of D, L-mandelic acid | CHONGQING UNISPLENDOUR INTERNAT CHEMICAL CO LTD | 2014-06-25 | — | — | CN | disclosed |
| CN-100445375-C | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AG (DE) | 2008-12-24 | — | — | CN | disclosed |
| CN-1753990-A | Modified nitrilases and their use in methods for the production of carboxylic acids | BASF AG (DE) | 2006-03-29 | — | — | CN | disclosed |