Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27660328 | 0.88 | HSD11B1 (0.35) | LMNAHSD11B1MAOBAKR1C1 | |
| SCHEMBL28551028 | 0.84 | HTT (0.33) | — | |
| SCHEMBL7588416 | 0.81 | LMNA (0.35) | LMNAPOLBCYP3A4PARP1MAPT | |
| Urea SCHEMBL10593912 | 0.80 | MAOB (0.32) | LMNAPOLBCYP3A4PARP1MAPT | |
| SCHEMBL27621152 | 0.79 | LMNA (0.33) | LMNAPOLBCYP3A4PARP1MAPT | |
| SCHEMBL7340572 | 0.79 | HTT (0.33) | LMNAPOLBCYP3A4PARP1MAPT | |
| SCHEMBL8330201 | 0.78 | LMNA (0.31) | LMNA | |
| SCHEMBL8752629 | 0.75 | MAOB (0.32) | MAOB | |
| SCHEMBL15389098 | 0.75 | MAOB (0.34) | LMNAMAOB | |
| SCHEMBL15346092 | 0.75 | KDM1A (0.30) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1745049-A | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2006-03-08 | — | — | CN | disclosed |