Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27648178 | 0.78 | LMNA (0.34) | LMNA | |
| SCHEMBL7340572 | 0.77 | HTT (0.33) | LMNA | |
| SCHEMBL7588416 | 0.76 | LMNA (0.35) | LMNA | |
| SCHEMBL27621152 | 0.74 | LMNA (0.33) | LMNA | |
| SCHEMBL15389098 | 0.71 | MAOB (0.34) | LMNA | |
| SCHEMBL27660328 | 0.70 | HSD11B1 (0.35) | LMNA | |
| SCHEMBL27615842 | 0.68 | OPRM1 (0.32) | — | |
| SCHEMBL8809639 | 0.67 | HCAR3 (0.31) | — | |
| SCHEMBL19032029 | 0.67 | CYP2C19 (0.37) | LMNA | |
| SCHEMBL28551028 | 0.67 | HTT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948800-A | 2-PHENYL-1,2-BENZISOSELENAZOL-3(2H)-ONE | A. NATTERMANN & CIE. GMBH (DE) | 1999-09-07 | — | — | US | disclosed |
| US-4757063-A | Administering 2-phenyl-1,2-benzisoselenazol-3(2H)-one | A. NATTERMANN & CIE. GMBH (DE) | 1988-07-12 | — | — | US | disclosed |
| EP-0249735-A2 | Pharmaceutical preparations comprising as active agent 2-phenyl-1.2-benzisoselenazol-3(2H)-one, for the treatment of diseases caused by oxidative stress | A. Nattermann & Cie. GmbH (DE) | 1987-12-23 | — | — | EP | disclosed |