Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648975 | 0.83 | CHRM3 (0.43) | CHRM3CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL4404703 | 0.81 | CYP2C9 (0.40) | CHRM3CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL27642911 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KDM4ECHRM3CHRM1CHRM2 | |
| SCHEMBL21057815 | 0.69 | CHRM3 (0.34) | CHRM3 | |
| SCHEMBL5712868 | 0.69 | CHRNA7 (0.42) | CHRM3CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL8529192 | 0.68 | CYP2C9 (0.38) | CHRM3CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL9145163 | 0.68 | CYP2C9 (0.38) | CHRM3CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL9146133 | 0.68 | CYP2C9 (0.38) | CHRM3CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL9848240 | 0.67 | CHRM3 (0.33) | CHRM3CHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL9145118 | 0.67 | CHRM3 (0.33) | CHRM3CHRM1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101913973-A | Preparation and use of alkylating agents | QUEENS MEDICAL CT | 2010-12-15 | — | — | CN | claimed |
| CN-1886362-A | Preparation and use of alkylating agents | QUEENS MEDICAL CT (US) | 2006-12-27 | — | — | CN | claimed |
| CN-101913973-B | Preparation and use of alkylating agents | QUEENS MEDICAL CT | 2013-11-20 | — | — | CN | disclosed |
| CN-101913973-A | Preparation and use of alkylating agents | QUEENS MEDICAL CT | 2010-12-15 | — | — | CN | disclosed |