Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 10/20 | 0.59 |
| ▸ | NMT1 | P30419 | 10/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27669293 | 0.89 | EDNRA (0.54) | NMT2NMT1NPC1RAB9AKDM4E | |
| SCHEMBL27649066 | 0.85 | NMT2 (0.51) | NMT2NMT1NPC1RAB9AKDM4E | |
| SCHEMBL6873768 | 0.85 | NPC1 (0.63) | NMT2NMT1NPC1RAB9AKDM4E | |
| SCHEMBL3617244 | 0.81 | NPC1 (0.65) | NMT2NMT1NPC1RAB9AKDM4E | |
| SCHEMBL1472922 | 0.80 | KDM4E (0.52) | NPC1RAB9AKDM4EHSD17B10MAPT | |
| SCHEMBL3609306 | 0.77 | NPC1 (0.76) | NMT2NMT1NPC1RAB9AKDM4E | |
| SCHEMBL5584822 | 0.74 | EDNRA (0.51) | NMT2NMT1NPC1RAB9AKDM4E | |
| SCHEMBL3609719 | 0.74 | NMT2 (0.73) | NMT2NMT1NPC1RAB9AKDM4E | |
| SCHEMBL12191227 | 0.74 | HRH3 (0.70) | ADRB2HRH3 | |
| SCHEMBL6863214 | 0.74 | NMT2 (0.55) | NMT2NMT1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100469780-C | Cysteine protease inhibitors | MEDIVIR AB (SE) | 2009-03-18 | — | — | CN | disclosed |
| CN-1918169-A | Cysteine protease inhibitors | MEDIVIR AB (SE) | 2007-02-21 | — | — | CN | disclosed |