Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.54 |
| ▸ | NMT2 | O60551 | 1/20 | 0.45 |
| ▸ | NMT1 | P30419 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27648970 | 0.89 | NMT2 (0.59) | NMT2NMT1HRH3KDM4ENPC1 | |
| SCHEMBL3617915 | 0.80 | EDNRA (0.65) | EDNRANMT2NMT1KDM4ENPC1 | |
| SCHEMBL27648961 | 0.80 | IRAK4 (0.45) | IRAK4HRH3DRD4KDREPHA2 | |
| SCHEMBL5288124 | 0.79 | KDM4E (0.57) | HRH3KDM4ENPC1RAB9A | |
| SCHEMBL1475583 | 0.79 | KDM4E (0.57) | HRH3KDM4ENPC1RAB9A | |
| SCHEMBL5287827 | 0.79 | KDM4E (0.57) | HRH3KDM4ENPC1RAB9A | |
| SCHEMBL5584822 | 0.77 | EDNRA (0.51) | EDNRANMT2NMT1KDM4ENPC1 | |
| SCHEMBL27649066 | 0.74 | NMT2 (0.51) | NMT2NMT1EPHA2EPHB4KDM4E | |
| SCHEMBL3612478 | 0.73 | EDNRA (0.73) | EDNRANMT2NMT1KDM4ENPC1 | |
| SCHEMBL6863935 | 0.73 | NMT2 (0.77) | EDNRANMT2NMT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100469780-C | Cysteine protease inhibitors | MEDIVIR AB (SE) | 2009-03-18 | — | — | CN | disclosed |
| CN-1918169-A | Cysteine protease inhibitors | MEDIVIR AB (SE) | 2007-02-21 | — | — | CN | disclosed |