Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 9/20 | 0.51 |
| ▸ | NMT1 | P30419 | 9/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27648970 | 0.85 | NMT2 (0.59) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL27669249 | 0.84 | EPHA2 (0.49) | NMT2NMT1ALDH1A1EPHA2ERBB2 | |
| SCHEMBL8251140 | 0.82 | KDM4E (0.47) | KDM4EHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL1473531 | 0.82 | KDM4E (0.47) | KDM4EHSD17B10MEN1USP2ALDH1A1 | |
| SCHEMBL28851224 | 0.80 | EPHA2 (0.51) | ALDH1A1EPHA2ERBB2EPHB4 | |
| SCHEMBL6873768 | 0.79 | NPC1 (0.63) | NMT2NMT1ADRB2ADRB1ADRB3 | |
| SCHEMBL13482008 | 0.77 | EPHA2 (0.51) | EPHA2ERBB2EPHB4 | |
| SCHEMBL4510923 | 0.76 | EPHA2 (0.54) | EPHA2ERBB2EPHB4 | |
| SCHEMBL15058458 | 0.76 | EPHA2 (0.52) | MEN1ALDH1A1KMT2AEPHA2ERBB2 | |
| SCHEMBL15058339 | 0.75 | EPHA2 (0.49) | EPHA2ERBB2EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100469780-C | Cysteine protease inhibitors | MEDIVIR AB (SE) | 2009-03-18 | — | — | CN | disclosed |
| CN-1918169-A | Cysteine protease inhibitors | MEDIVIR AB (SE) | 2007-02-21 | — | — | CN | disclosed |