Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1473531 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1RAB9ANPC1TSHR | |
| SCHEMBL5294746 | 0.91 | KDM4E (0.51) | KDM4ERAB9ANPC1EPHA2SMN1; SMN2 | |
| SCHEMBL1472922 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1RAB9ANPC1TSHR | |
| SCHEMBL5292472 | 0.84 | EPHA2 (0.43) | EPHA2ERBB2EPHB4 | |
| SCHEMBL5297191 | 0.84 | EPHA2 (0.43) | EPHA2ERBB2EPHB4 | |
| SCHEMBL1473383 | 0.84 | EPHA2 (0.43) | EPHA2ERBB2EPHB4 | |
| SCHEMBL27649066 | 0.82 | NMT2 (0.51) | KDM4EALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL5293248 | 0.80 | USP2 (0.49) | KDM4EALDH1A1RAB9ANPC1TSHR | |
| SCHEMBL9214625 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL27669249 | 0.78 | EPHA2 (0.49) | ALDH1A1EPHA2ERBB2EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006714-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007006715-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-01-18 | — | — | WO | disclosed |