Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6384766 | 1.00 | CTSK (0.55) | CTSKHTTCTSLCTSSSIRT5 | |
| SCHEMBL6383945 | 0.89 | CTSK (0.66) | CTSKCTSLCTSSSIRT5CAPN1 | |
| SCHEMBL10035721 | 0.88 | CTSK (0.55) | CTSKCTSLCTSSPSMB8PSMB9 | |
| SCHEMBL10035700 | 0.88 | CTSK (0.55) | CTSKCTSLCTSSPSMB8PSMB9 | |
| SCHEMBL6384215 | 0.87 | CTSL (0.66) | CTSKCTSLCTSSSIRT5CTSB | |
| SCHEMBL27649629 | 0.87 | CTSL (0.66) | CTSKCTSLCTSSSIRT5CTSB | |
| SCHEMBL29372806 | 0.86 | MME (0.61) | CTSKFOLH1CAPN1PSMB8PSMB9 | |
| SCHEMBL31243057 | 0.84 | CTSL (0.57) | CTSKHTTCTSLCTSSSIRT5 | |
| SCHEMBL31243031 | 0.84 | SIRT2 (0.62) | CTSKHTTCTSLCTSSSIRT5 | |
| SCHEMBL9359914 | 0.84 | CTSK (0.60) | CTSKCTSLCTSSCAPN1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1911921-A | Method for identification of tumor targeting enzymes | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2007-02-14 | — | — | CN | disclosed |