Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.66 |
| ▸ | TACR1 | P25103 | 2/20 | 0.60 |
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | CTSS | P25774 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 1/20 | 0.59 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6384215 | 1.00 | CTSL (0.66) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL8668091 | 0.89 | TACR1 (0.70) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL30902878 | 0.88 | MME (0.56) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL6383945 | 0.87 | CTSK (0.66) | CTSLCTSBCTSSCTSKSIRT5 | |
| SCHEMBL27649586 | 0.87 | CTSK (0.55) | CTSLCTSBCTSSCTSKSIRT5 | |
| SCHEMBL6384766 | 0.87 | CTSK (0.55) | CTSLCTSBCTSSCTSKSIRT5 | |
| SCHEMBL10397579 | 0.87 | MME (0.67) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL31243057 | 0.85 | CTSL (0.57) | CTSLCTSSCTSKSIRT5 | |
| SCHEMBL31243031 | 0.85 | SIRT2 (0.62) | CTSLCTSSCTSKSIRT5 | |
| SCHEMBL6278137 | 0.85 | FOLH1 (0.67) | CTSLCTSSSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1911921-A | Method for identification of tumor targeting enzymes | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2007-02-14 | — | — | CN | disclosed |