Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 3/20 | 0.37 |
| ▸ | METAP1 | P53582 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29193788 | 0.83 | RAB9A (0.40) | RAB9AALDH1A1METAP2METAP1IDO1 | |
| Hydrochloric Acid SCHEMBL28439612 | 0.82 | RAB9A (0.39) | RAB9AALDH1A1METAP2METAP1IDO1 | |
| SCHEMBL25218721 | 0.80 | RAB9A (0.38) | RAB9AALDH1A1METAP2METAP1IDO1 | |
| SCHEMBL25195699 | 0.80 | ALDH1A1 (0.38) | RAB9AALDH1A1METAP2METAP1IDO1 | |
| SCHEMBL13324245 | 0.73 | MCHR1 (0.32) | — | |
| SCHEMBL5598756 | 0.72 | ROCK2 (0.30) | — | |
| SCHEMBL1726398 | 0.72 | RAB9A (0.38) | RAB9AALDH1A1METAP2METAP1IDO1 | |
| SCHEMBL1726180 | 0.72 | RAB9A (0.38) | RAB9AALDH1A1METAP2METAP1IDO1 | |
| SCHEMBL7108204 | 0.72 | — | — | |
| SCHEMBL2150833 | 0.69 | ALDH1A1 (0.39) | RAB9AALDH1A1METAP2METAP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1823048-A | Substituted pyrimidin-4-ylamina analogues as vanilloid receptor ligands | NEUROGEN CORP (US) | 2006-08-23 | — | — | CN | disclosed |