Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.82 |
| ▸ | USP7 | Q93009 | 8/20 | 0.62 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 4/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487830 | 0.90 | MET (1.00) | METUSP7MAP4K4FYNCHEK2 | |
| SCHEMBL30453987 | 0.90 | MET (1.00) | METUSP7MAP4K4FYNCHEK2 | |
| SCHEMBL27650092 | 0.89 | MET (0.69) | METUSP7MAP4K4FYNPTGER1 | |
| SCHEMBL487522 | 0.89 | MET (0.72) | METUSP7MAP4K4FYNPTGER1 | |
| SCHEMBL30452575 | 0.89 | MET (0.72) | METUSP7MAP4K4FYNPTGER1 | |
| SCHEMBL6361398 | 0.85 | MET (0.69) | METUSP7MAP4K4PTGER1PTGER4 | |
| SCHEMBL487729 | 0.84 | MET (0.65) | METUSP7MAP4K4PTGER1PTGER4 | |
| SCHEMBL30453367 | 0.84 | MET (0.65) | METUSP7MAP4K4PTGER1PTGER4 | |
| SCHEMBL488125 | 0.83 | MET (0.63) | METUSP7MAP4K4FYNTGFBR1 | |
| SCHEMBL30453937 | 0.83 | MET (0.63) | METUSP7MAP4K4FYNTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | claimed |