Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.63 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 6/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488125 | 1.00 | MET (0.63) | METCHRNA7FYNPDGFRBPDGFRA | |
| SCHEMBL487962 | 0.87 | MET (0.62) | METMAP4K4USP7MAP4K3PTGER1 | |
| SCHEMBL487821 | 0.86 | MET (0.61) | METCHRNA7FYNMAP4K4USP7 | |
| SCHEMBL30454267 | 0.85 | MET (0.60) | METCHRNA7USP7MAP4K3PTGER1 | |
| SCHEMBL487806 | 0.85 | MET (0.60) | METCHRNA7USP7MAP4K3PTGER1 | |
| SCHEMBL6361398 | 0.85 | MET (0.69) | METEPHB4MAP4K4USP7MAP4K3 | |
| SCHEMBL487522 | 0.84 | MET (0.72) | METCHRNA7FYNMAP4K4USP7 | |
| SCHEMBL487729 | 0.84 | MET (0.65) | METMAP4K4USP7MAP4K3PTGER1 | |
| SCHEMBL30453367 | 0.84 | MET (0.65) | METMAP4K4USP7MAP4K3PTGER1 | |
| SCHEMBL30452575 | 0.84 | MET (0.72) | METCHRNA7FYNMAP4K4USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |