Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.72 |
| ▸ | USP7 | Q93009 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487522 | 1.00 | MET (0.72) | METUSP7MAP4K4PTGER1PTGER4 | |
| SCHEMBL27650092 | 0.95 | MET (0.69) | METUSP7MAP4K4PTGER1PTGER4 | |
| SCHEMBL27650091 | 0.89 | MET (0.82) | METUSP7MAP4K4PTGER1PTGER4 | |
| SCHEMBL6361398 | 0.86 | MET (0.69) | METUSP7MAP4K4PTGER1PTGER4 | |
| SCHEMBL487729 | 0.85 | MET (0.65) | METUSP7MAP4K4PTGER1PTGER4 | |
| SCHEMBL30453367 | 0.85 | MET (0.65) | METUSP7MAP4K4PTGER1PTGER4 | |
| SCHEMBL488125 | 0.84 | MET (0.63) | METUSP7MAP4K4PTGER1PTGER4 | |
| SCHEMBL30453937 | 0.84 | MET (0.63) | METUSP7MAP4K4PTGER1PTGER4 | |
| SCHEMBL487830 | 0.84 | MET (1.00) | METUSP7MAP4K4MPOMAP4K3 | |
| SCHEMBL30453987 | 0.84 | MET (1.00) | METUSP7MAP4K4MPOMAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |