Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | MET | P08581 | 2/20 | 0.48 |
| ▸ | USP7 | Q93009 | 4/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30454226 | 0.86 | MET (0.57) | MAP4K4METUSP7PLAUFYN | |
| SCHEMBL487901 | 0.86 | MET (0.57) | MAP4K4METUSP7PLAUFYN | |
| SCHEMBL27650119 | 0.80 | MET (0.54) | MAP4K4METFYNTGFBR1 | |
| SCHEMBL30453829 | 0.77 | MET (0.55) | MAP4K4METUSP7PLAUFYN | |
| SCHEMBL488435 | 0.77 | MET (0.55) | MAP4K4METUSP7PLAUFYN | |
| SCHEMBL28758853 | 0.75 | MET (0.52) | MAP4K4MET | |
| SCHEMBL487828 | 0.74 | MAP4K4 (0.69) | MAP4K4METXDH | |
| SCHEMBL30453543 | 0.74 | MAP4K4 (0.69) | MAP4K4METXDH | |
| SCHEMBL487657 | 0.72 | MET (0.75) | MAP4K4METUSP7FYNTGFBR1 | |
| SCHEMBL30452824 | 0.72 | MET (0.75) | MAP4K4METUSP7FYNTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | claimed |