Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 8/20 | 0.69 |
| ▸ | MET | P08581 | 4/20 | 0.62 |
| ▸ | XDH | P47989 | 3/20 | 0.51 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487828 | 1.00 | MAP4K4 (0.69) | MAP4K4METXDHALKBH1CSNK2A2 | |
| SCHEMBL488435 | 0.89 | MET (0.55) | MAP4K4METKDM4EALDH1A1 | |
| SCHEMBL30453829 | 0.89 | MET (0.55) | MAP4K4METKDM4EALDH1A1 | |
| SCHEMBL487901 | 0.88 | MET (0.57) | MAP4K4METKDM4EALDH1A1 | |
| SCHEMBL30454226 | 0.88 | MET (0.57) | MAP4K4METKDM4EALDH1A1 | |
| SCHEMBL27630101 | 0.85 | ALDH1A1 (0.61) | MAP4K4METXDHALKBH1KDM4E | |
| SCHEMBL30452541 | 0.84 | MET (0.66) | MAP4K4MET | |
| SCHEMBL487715 | 0.84 | MET (0.66) | MAP4K4MET | |
| SCHEMBL30454971 | 0.84 | MAP4K4 (0.73) | MAP4K4METALKBH1 | |
| SCHEMBL487832 | 0.84 | MAP4K4 (0.73) | MAP4K4METALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |