Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488435 | 1.00 | MET (0.55) | METMAP4K4PLAUALDH1A1NPSR1 | |
| SCHEMBL487901 | 0.91 | MET (0.57) | METMAP4K4PLAUALDH1A1KDM4E | |
| SCHEMBL30454226 | 0.91 | MET (0.57) | METMAP4K4PLAUALDH1A1KDM4E | |
| SCHEMBL30453543 | 0.89 | MAP4K4 (0.69) | METMAP4K4ALDH1A1KDM4E | |
| SCHEMBL487828 | 0.89 | MAP4K4 (0.69) | METMAP4K4ALDH1A1KDM4E | |
| SCHEMBL6424806 | 0.85 | MET (0.52) | METMAP4K4PLAUALDH1A1KDM4E | |
| SCHEMBL488273 | 0.83 | PLAU (0.51) | METPLAUALDH1A1KDM4ESGMS2 | |
| SCHEMBL487629 | 0.83 | MET (0.51) | METMAP4K4PLAUFYNSGMS2 | |
| SCHEMBL488082 | 0.80 | MET (0.61) | METMAP4K4FYNMAP4K3USP7 | |
| SCHEMBL30452541 | 0.79 | MET (0.66) | METMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |