Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 7/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452546 | 0.83 | MPO (0.44) | MPOKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL488920 | 0.83 | MPO (0.44) | MPOKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL27650223 | 0.81 | GRIN2B (0.37) | MPOKDM4ES1PR1 | |
| SCHEMBL27630118 | 0.67 | S1PR1 (0.34) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL27650140 | 0.67 | S1PR1 (0.35) | MPOKDM4EALDH1A1HSD17B10S1PR1 | |
| SCHEMBL10216305 | 0.66 | CSF1R (0.37) | MPOKDM4ES1PR1ICMT | |
| SCHEMBL30453037 | 0.66 | CSF1R (0.37) | MPOKDM4ES1PR1ICMT | |
| SCHEMBL488448 | 0.66 | CSF1R (0.37) | MPOKDM4ES1PR1ICMT | |
| SCHEMBL21724167 | 0.66 | MPO (0.68) | MPOKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL30453085 | 0.66 | S1PR1 (0.41) | MPOKDM4ES1PR1HTR1DICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | disclosed |