Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.44 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 6/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 6/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488920 | 1.00 | MPO (0.44) | MPOCSF1RPIM1PIM3PIM2 | |
| SCHEMBL27650232 | 0.83 | MPO (0.44) | MPOPIM1PIM3PIM2KDM4E | |
| SCHEMBL488054 | 0.83 | S1PR1 (0.41) | MPOCSF1RKDM4EICMTMET | |
| SCHEMBL30453085 | 0.83 | S1PR1 (0.41) | MPOCSF1RKDM4EICMTMET | |
| SCHEMBL488471 | 0.82 | S1PR1 (0.41) | MPOCSF1RKDM4EICMTMET | |
| SCHEMBL30453674 | 0.82 | S1PR1 (0.41) | MPOCSF1RKDM4EICMTMET | |
| SCHEMBL30453800 | 0.81 | LRRK2 (0.41) | MPOCSF1RMETS1PR1 | |
| SCHEMBL488507 | 0.81 | LRRK2 (0.41) | MPOCSF1RMETS1PR1 | |
| SCHEMBL488448 | 0.80 | CSF1R (0.37) | MPOCSF1RKDM4EICMTMET | |
| SCHEMBL30453037 | 0.80 | CSF1R (0.37) | MPOCSF1RKDM4EICMTMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |