Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 3/20 | 0.47 |
| ▸ | MET | P08581 | 3/20 | 0.46 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27650178 | 0.95 | ALK (0.53) | ALKMETINPPL1ACHENTRK1 | |
| SCHEMBL488088 | 0.84 | ALK (0.54) | ALKMETINPPL1ACHENTRK1 | |
| SCHEMBL488016 | 0.79 | ALK (0.61) | ALKMETINPPL1NTRK1 | |
| SCHEMBL30452658 | 0.79 | ALK (0.61) | ALKMETINPPL1NTRK1 | |
| SCHEMBL487940 | 0.78 | ALK (0.72) | ALKMET | |
| SCHEMBL31672562 | 0.78 | MET (0.44) | ALKMETINPPL1ACHENTRK1 | |
| SCHEMBL30453916 | 0.78 | ALK (0.72) | ALKMET | |
| SCHEMBL488154 | 0.77 | ALK (0.49) | ALKMETACHENTRK1BCHE | |
| SCHEMBL30452612 | 0.77 | ALK (0.49) | ALKMETACHENTRK1BCHE | |
| SCHEMBL27630100 | 0.75 | MET (0.60) | METACHEBCHEMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | disclosed |