Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30454537 | 0.81 | MET (0.70) | METNPC1RAB9AACHEBCHE | |
| SCHEMBL488104 | 0.81 | MET (0.70) | METNPC1RAB9AACHEBCHE | |
| SCHEMBL27630240 | 0.76 | MET (0.49) | METACHEKDM4EALDH1A1KDR | |
| SCHEMBL27650178 | 0.75 | ALK (0.53) | METNPC1ACHEBCHEMAOA | |
| SCHEMBL27629910 | 0.75 | CSF1R (0.42) | METNPC1RAB9AKDM4E | |
| SCHEMBL27650243 | 0.75 | ALK (0.47) | METNPC1RAB9AACHEBCHE | |
| SCHEMBL487596 | 0.75 | MET (1.00) | METNPC1RAB9AACHEBCHE | |
| SCHEMBL487852 | 0.73 | MET (0.65) | METNPC1RAB9AACHEBCHE | |
| SCHEMBL30454825 | 0.73 | MET (0.65) | METNPC1RAB9AACHEBCHE | |
| SCHEMBL210766 | 0.70 | NPC1 (0.57) | METNPC1RAB9AACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | claimed |