Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 4/20 | 0.61 |
| ▸ | MET | P08581 | 13/20 | 0.58 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.53 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488016 | 1.00 | ALK (0.61) | ALKMETMAP4K3INPPL1JAK2 | |
| SCHEMBL488088 | 0.95 | ALK (0.54) | ALKMETMAP4K3INPPL1NTRK1 | |
| SCHEMBL30452612 | 0.89 | ALK (0.49) | ALKMETMAP4K3NTRK1 | |
| SCHEMBL488154 | 0.89 | ALK (0.49) | ALKMETMAP4K3NTRK1 | |
| SCHEMBL488401 | 0.85 | ALK (0.80) | ALKMETJAK2 | |
| SCHEMBL30453722 | 0.85 | ALK (0.80) | ALKMETJAK2 | |
| SCHEMBL488802 | 0.84 | MET (0.66) | ALKMETMAP4K3 | |
| SCHEMBL30454806 | 0.84 | MET (0.66) | ALKMETMAP4K3 | |
| SCHEMBL27650178 | 0.84 | ALK (0.53) | ALKMETINPPL1NTRK1 | |
| SCHEMBL5486840 | 0.80 | MAP4K3 (0.62) | ALKMETMAP4K3INPPL1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |